Dr. Tyler S. Ralston

Senior Member | CTO
Ralston, Tyler S.
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SPIE Membership: 13.3 years
SPIE Awards: Senior status
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Social Media: LinkedIn
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Profile Summary


Tyler Ralston, Ph.D. is an engineering entrepreneur who has founded a number of companies and dedicated his career to finding solutions for patient care and early detection of disease. Leveraging his deep knowledge in imaging technologies, Tyler has helped drive the technical developments as CTO at ONI, with super-resolution microscopy; Butterfly Network, with handheld ultrasound-on-chip imaging devices; Hyperfine, with a breakthrough portable MRI machine; as well as Tesseract Health, with portable retinal imaging systems. As an early founder, he has been instrumental in raising more than $500+M in investment from seed through to going public (BFLY/HYPR). These medical innovations garnered prolific awards and recognition, such as the front page of New York Times, Time – Best Inventions, Apple Design, Fast Co., Fortune, RSNA, CES, SxSW, and more. Prior to these accomplishments, he has been at Battelle, developing several R&D 100 award-winning instruments, including an automated microscope to detect cancer cells in pap tests, a gamma-ray detection console for surgical guidance, and an automated white blood cell analysis microscope. Tyler continued his work across multiple modalities at Beckman Institute, MIT Lincoln Laboratory, and Lawrence Livermore National Laboratory, where he developed technologies and drove projects in 3D optical coherence tomography, multi-static 3D radar, 3D electro optic, and 3D gamma ray imaging. Tyler is an author and/or co-author of 100+ patents, 50+ papers with 5400+ citations, 3 book contributions with 42 presentations at international conferences, and 20+ invited presentations. Tyler received his Ph.D. in Electrical and Computer Engineering at the University of Illinois at Urbana-Champaign, where he developed Interferometric Synthetic Aperture Microscopy (ISAM), real-time phase-stable computational optical coherence tomography systems for cancer tissue surveillance.

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