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Proceedings Paper

Spectrometer based Fourier domain optical coherence tomography of the mouse retina
Author(s): Jing Xu; Mohammadali H. Khorasani; Jimmy N. B. Koo; Marinko V. Sarunic
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Paper Abstract

We present a custom Fourier Domain Optical Coherence Tomography (FDOCT) system adapted to imaging the retinal structures in mice. The FDOCT system utilized spectrometer detection, and operated at a central wavelength of 826nm with a FWHM spectral bandwidth of 72nm, corresponding to an axial resolution of ~4microns (in air). A custom hand-held probe was constructed providing adjustable focusing and increased maneuverability over fixed systems to facilitate coupling of the raster scanned beam into the mouse eye. Image acquisition and display was performed in real time using custom written, multi-threaded software package which displays two dimensional B-scans. Cross sectional images of mouse retina, acquired in vivo an anesthetized animals, are presented.

Paper Details

Date Published: 18 February 2008
PDF: 7 pages
Proc. SPIE 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, 684731 (18 February 2008); doi: 10.1117/12.766069
Show Author Affiliations
Jing Xu, Simon Fraser Univ. (Canada)
Mohammadali H. Khorasani, Simon Fraser Univ. (Canada)
Jimmy N. B. Koo, Simon Fraser Univ. (Canada)
Marinko V. Sarunic, Simon Fraser Univ. (Canada)

Published in SPIE Proceedings Vol. 6847:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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