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Proceedings Paper

Improved diagnostics by automated matching and enhancement in fluorescein angiography of the ocular fundus
Author(s): Herke Jan Noordmans; Pieter van den Biesen; Rowland de Roode; Rudolf Verdaasdonk
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Paper Abstract

An interactive image matching program has been developed to help ophthalmologists in perceiving subtle differences between sequential images obtained during fluorescein angiography. In a pilot experiment, it appeared that the image matching program could effectively correct camera alignment errors. By offering simple tools like image overlay, blinking and image subtraction, differences between angiograms can be greatly enhanced and interpreted. It appeared that newly formed, leaking blood vessels could be detected at an earlier stage of the disease process using these tools. Treatment can be initiated right away, thereby preventing the patient from having additional visual loss. The matching program seems to improve the quality of fundus diagnostics but needs to be validated in future studies.

Paper Details

Date Published: 25 February 2008
PDF: 8 pages
Proc. SPIE 6844, Ophthalmic Technologies XVIII, 68440G (25 February 2008); doi: 10.1117/12.762978
Show Author Affiliations
Herke Jan Noordmans, Univ. Medisch Ctr. Utrecht (Netherlands)
Pieter van den Biesen, Univ. Medisch Ctr. Utrecht (Netherlands)
Rowland de Roode, Univ. Medisch Ctr. Utrecht (Netherlands)
Rudolf Verdaasdonk, Univ. Medisch Ctr. Utrecht (Netherlands)

Published in SPIE Proceedings Vol. 6844:
Ophthalmic Technologies XVIII
Bruce E. Stuck; Fabrice Manns; Per G. Söderberg; Michael Belkin M.D.; Arthur Ho, Editor(s)

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