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Proceedings Paper

Simulating nodules in chest radiographs with real nodules from multi-slice CT images
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Paper Abstract

To improve the detection of nodules in chest radiographs, large databases of chest radiographs with annotated, proven nodules are needed for training of both radiologists and computer-aided detection systems. The construction of such databases is a laborious and time-consuming task. This study presents a novel technique to produce large amounts of chest x-rays with annotated, simulated nodules. Realistic nodules in radiographs are generated using real nodules segmented from CT images. Results from an observer study indicate that the simulated nodules can not be distinguished from real nodules. This method has great potential to aid the development of automated detection systems and to generate teaching files for human observers.

Paper Details

Date Published: 15 March 2006
PDF: 8 pages
Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 614456 (15 March 2006); doi: 10.1117/12.651623
Show Author Affiliations
Arnold Schilham, Image Sciences Institute, Univ. Medical Ctr. Utrecht (Netherlands)
Bram van Ginneken, Image Sciences Institute, Univ. Medical Ctr. Utrecht (Netherlands)

Published in SPIE Proceedings Vol. 6144:
Medical Imaging 2006: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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