Dr. Osman O. Ahsen

I have done my graduate research in the research group that pioneered the development of Optical Coherence Tomography (OCT) imaging technology. During my tenure at the MIT, I have made contributions to several OCT and fluorescence imaging technologies including swept source-OCT, Optical Coherence Microscopy and Nonlinear Imaging Microscopy. These imaging devices were developed in a highly collaborative setting involving clinical collaborators at the VA Boston Healthcare System and Beth Israel Deaconess Medical Center, as well as our industrial partners at the Thorlabs, Inc and Praevium Research, Inc. I got the opportunity to work on throughout the various stages of medical device development pipeline, which involved development of basic technology, demonstrating its safety and effectiveness in preclinical settings, obtaining regulatory approvals for in human testing and finally conducting large-scale human studies to assess clinical utility. Recently, I joined Dr. Guillermo J. Tearney’s group at Wellman Center at the MGH, and have shifted my focus to intravascular imaging. In Dr. Tearney’s group I am working on developing novel multi-modal intravascular imaging technologies aimed to improve clinical management of coronary artery disease, by combining an array of technologies such as OCT, near-infrared fluorescence and near-infrared autofluorescence (NIRAF) imaging, and endothelial shear stress measurement methods.