Charles Maphanga

Student Member | Doctoral Candidate at Council for Scientific and Industrial Research
Maphanga, Charles
SPIE Leadership: Retrieving Data, please wait...
SPIE Membership: 3.3 years total | 0.0 years voting
SPIE Involvement: Retrieving Data, please wait...
Area of Expertise: Human Immunideficiecy Virus (HIV), Femtosecond laser, Optical drug translocation, Microfluidics, Optical trapping and sorting, Point-of-Care (POC) diagnostic devices
Websites: Company Website
Social Media: Twitter | LinkedIn
Contact Details:
Sign In to send a private message or view contact details

Profile Summary

My masters research topic primarily focused on the use of laser technology as an alternative technique for administering drugs (medicines) into the human body in a targeted manner other than using the conventional enteral and parenteral routes of drug administration. I used a pulsed femtosecond laser with high peak power and ultra-short pulses to create a sub-microscopic pore on the cell membrane of HIV-l infected cells (in-vitro) in the presence of antiretroviral (ARV) drugs, and further performed cell viability, cytotoxicity, and HIV-1 infection levels post laser-enhanced drug delivery using molecular biology assays. Currently I am still in the early stages of my PhD degree. In this new exciting adventure I am using microfluidics approach integrated to a laser device in order to design and fabricate a laser-based Point-of-Care (POC) device for real-time HIV qualitative and quantitative testing. This device will be very beneficial especially in resource-limited settings and developing countries.

SPIE Volunteer Activities

Retrieving Data, please wait...

Upcoming Presentations

Most Recent | Show All
Retrieving Data, please wait...


Most Recent | Show All
Retrieving Data, please wait...

Conference Committee Involvement

Most Recent | Show All
Retrieving Data, please wait...

Course Instructor

Most Recent | Show All
Retrieving Data, please wait...
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?