The feasibility of multi-mode fiber based speckle contrast optical spectroscopy

Chen-Hao P. Lin; Inema E. Orukari; Christopher Tracy; Manish Verma; Lisa Kobayashi Frisk; Sumana Chetia; Jason W. Trobaugh; Turgut Durduran; Joseph P. Culver

doi:10.1117/12.2578523

5 March 2021 The feasibility of multi-mode fiber based speckle contrast optical spectroscopy

Chen-Hao P. Lin, Inema E. Orukari, Christopher Tracy, Manish Verma, Lisa Kobayashi Frisk, Sumana Chetia, Jason W. Trobaugh, Turgut Durduran, Joseph P. Culver

Author Affiliations +

Proceedings Volume 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII; 116410M (2021) https://doi.org/10.1117/12.2578523
Event: SPIE BiOS, 2021, Online Only

Abstract

Speckle contrast optical spectroscopy/tomography (SCOS/SCOT) is a low-cost, non-invasive, and real-time optical imaging modality for measuring cerebral blood flow with increased signal-to-noise ratio relative to diffuse correlation spectroscopy. However, the recent camera-based detector system is not ideal for imaging a large area of the human brain because of the limited area of focus over the contour of the head and hair occluding the field of view. Here we demonstrated the feasibility of using inexpensive multi-mode fiber bundles to build a SCOS system for mapping the flow of fluids, and we showed a statistical method for distinguishing noise and speckle signals.

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Chen-Hao P. Lin, Inema E. Orukari, Christopher Tracy, Manish Verma, Lisa Kobayashi Frisk, Sumana Chetia, Jason W. Trobaugh, Turgut Durduran, and Joseph P. Culver "The feasibility of multi-mode fiber based speckle contrast optical spectroscopy", Proc. SPIE 11641, Dynamics and Fluctuations in Biomedical Photonics XVIII, 116410M (5 March 2021); https://doi.org/10.1117/12.2578523

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