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Conference 13006 > Paper 13006-79
Paper 13006-79

Rapid measurement of epidermal thickness with a 1.6 MHz FDML OCT system

On demand | Presented live 9 April 2024

Abstract

Atopic dermatitis (AD), characterized by itchiness and inflammation, often results in increased skin thickness. Traditional treatments with topical corticosteroids may compound this effect. Addressing the need for accurate epidermal measurement and the slow acquisition times of previous methods, we developed a high-speed OCT system utilizing a 1.67 MHz FDML laser and a MEMS scanner, enabling 0.1-second scans that simplify patient compliance. The system has an axial resolution of 13-14 µm and a lateral resolution of 35 µm in air and a maximum field of view of 2.9 mm x 2.9 mm. An automatic segmentation algorithm was developed to delineate the skin surface and epidermal-dermal junction. Initial findings show the epidermal layer mostly ranges from 110 to 150 micrometers on dorsal hand skin, with a detailed epidermal thickness map for visualization of skin structure. A more efficient and patient-friendly approach is offered for evaluating AD severity and treatment response.

Presenter

The Univ. of Sheffield (United Kingdom)
I received my MEng degree in Optical Engineering from Huazhong University of Science and Technology in 2019. During my postgraduate studies, I focused on quantitative research using laser-induced breakdown spectroscopy (LIBS) and developed a single-sample calibration method to improve the detection accuracy for major elements in samples like steel. In October 2020, I started my PhD programme at the University of Sheffield in the EEE Biophotonics group led by Professor Stephen Matcher. My current project aims to develop a high-speed near-IR OCT functional angiography system for quantifying blood flow velocity in cutaneous blood vessels, which is a promising imaging method for guiding the treatment of atopic dermatitis (AD).
Presenter/Author
The Univ. of Sheffield (United Kingdom)
Author
The Univ. of Sheffield (United Kingdom)
Author
The Univ. of Sheffield (United Kingdom)
Author
The Univ. of Sheffield (United Kingdom)