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11-16 April 2026
Conference 13006 > Paper 13006-65
Paper 13006-65

Oil immersed single objective light sheet microscope

11 April 2024 • 16:10 - 16:30 CEST | Etoile B, Niveau/Level 1

Abstract

Imaging a large number of samples is necessary to improve statistical robustness in biological assays. Using standard multiwell plates is not possible in usual light-sheet microscopes. One solution is to use an Oblique Plane Microscope (OPM), which is a special fluorescence light sheet microscope, with a single objective near to the sample. To avoid aberrations, OPM generally uses water or silicon immersion to match the refractive index of the sample. In this work we present an oil-immersed OPM and experimentally demonstrate the possibility of using a primary objective with a higher numerical aperture.

Presenter

Quentin Bécar
ICube, Univ. de Strasbourg (France)
Presenter/Author
Quentin Bécar
ICube, Univ. de Strasbourg (France)
Author
ICube, Univ. de Strasbourg (France)
Author
ICube, Univ. de Strasbourg (France)
Author
ICube, Univ. de Strasbourg (France)