See you in two years!
11-16 April 2026
Conference 13006 > Paper 13006-5
Paper 13006-5

Biomedical CARS system free of external delay line

8 April 2024 • 14:00 - 14:20 CEST | Etoile B, Niveau/Level 1

Abstract

Multiplex Coherent Anti-Stokes Raman Scattering (M-CARS) is an innovative nonlinear spectroscopic approach designed to characterize the vibrational modes of molecular structures. Coherent Raman scattering has been used for the characterization of biomedical targets for about 20 years and the multiplex aspect was introduced 10 years ago thanks to the use of a supercontinuum laser system. For each of these systems, the combination of a pump and a probe wave, driven by an external delay line, is however required to produce the vibrations. In the present work, we propose a new M-CARS system, free of the external delay line. A few-mode microstructured fiber enables merging both wave-packets (pump and supercontinuum) within a single waveguide. We showcase the capability of this system in generating hyperspectral images of biochemically active compounds. Curcumin I, the principal yellow compound isolated from Curcuma longa (Turmeric), is distinguishable by its multiple functional groups that display a nonlinear spectroscopic behavior.

Presenter

Claire Lefort
XLIM, Univ. de Limoges (France)
Author
Tigran Mansuryan
XLIM, Univ. de Limoges (France)
Author
XLIM (France)
Author
Institute of Physical Chemistry (Poland)
Author
Univ. de Limoges (France)
Author
Univ. de Limoges (France)
Author
Univ. de Limoges (France)
Presenter/Author
Claire Lefort
XLIM, Univ. de Limoges (France)
Author
Sapienza Univ. di Roma (Italy)
Author
Mario Ferraro
Sapienza Univ. di Roma (Italy)
Author
Fabio Mangini
Univ. degli Studi di Brescia (Italy)
Author
Yifan Sun
Sapienza Univ. di Roma (Italy)
Author
Yago Arosa
XLIM (France), Univ. de Santiago de Compostela (Spain)
Author
Benjamin Wetzel
XLIM (France)
Author
Sapienza Univ. di Roma (Italy), Istituto Nazionale di Ottica, Consiglio Nazionale delle Ricerche (Italy)
Author
XLIM (France)