BDIC: boosting the performance of optical microscopy using blind deconvolution and illumination correction

Shuhe Zhang; Tos T. J. M. Berendschot; Jinhua Zhou; Meng Shao

doi:10.1117/12.2620781

17 May 2022 BDIC: boosting the performance of optical microscopy using blind deconvolution and illumination correction

Shuhe Zhang, Tos T. J. M. Berendschot, Jinhua Zhou, Meng Shao

Proceedings Volume 12138, Optics, Photonics and Digital Technologies for Imaging Applications VII; 121380E (2022) https://doi.org/10.1117/12.2620781
Event: SPIE Photonics Europe, 2022, Strasbourg, France

Abstract

We propose the combination of single image blind deconvolution and illumination correction (BDIC) to enhance the image quality of a microscopy system. We evaluated the performance this method by calculating the peak signal-to-noise ratio and structural similarity of both raw and enhanced images with respect to the reference images. Both subjective and objective assessments show that BDIC increases the image's quality including its contrast and signal-to-noise ratio, without losing image resolution and structural information. To demonstrate its applicability, we also applied BDIC to different samples including plant root tissue and human blood smears.

Conference Presentation

Citation Download Citation

Shuhe Zhang, Tos T. J. M. Berendschot, Jinhua Zhou, and Meng Shao "BDIC: boosting the performance of optical microscopy using blind deconvolution and illumination correction", Proc. SPIE 12138, Optics, Photonics and Digital Technologies for Imaging Applications VII, 121380E (17 May 2022); https://doi.org/10.1117/12.2620781

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