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Proceedings Paper • Open Access

Molecular-level engineering of THz/IR-sensitive materials for future biological sensing application

Paper Abstract

While the unique spectral information associated with chemical and biological molecules within the terahertz frequency regime (~ 3.0-3.0 millimeters) motivates its use for practical sensing applications, limiting factors at the macroscale (weak spectral absorption, broad line widths and masking geometrical effects introduced by the samples) provides motivation for man-engineered sensing materials that allow for the transduction of the spectral information about target molecules from the nanoscale. This brief letter will overview work being performed by our research group to define molecular-level functionality that will be useful for realizing "THz/IR-sensitive" materials. Here the goal is to define switchable molecular components that when incorporated into larger DNA-based nanoscaffolds lead to THz and/or IR regime electronic and/or photonic material properties that are dictated in a predictable manner by novel functionality paradigms. In particular, theoretical modeling and design studies are being performed to engineer organic and biological switches that can be incorporated into DNA-based architectures that enable the precise extraction of nanoscale information (e.g., composition, dynamics, conformation) through electronic/photonic transformations to the macroscale. Hence, these studies seek to define new spectral-based sensing modalities useful for characterizing bio-molecules

Paper Details

Date Published: 9 September 2010
PDF: 5 pages
Proc. SPIE 7763, Terahertz Emitters, Receivers, and Applications, 77630D (9 September 2010); doi: 10.1117/12.865580
Show Author Affiliations
Dwight Woolard, Army Research Office (United States)
North Carolina State Univ. (United States)
Gregory Recine, Fordham Univ. (United States)
North Carolina State Univ. (United States)
Alexei Bykhovski, North Carolina State Univ. (United States)
Weidong Zhang, North Carolina State Univ. (United States)

Published in SPIE Proceedings Vol. 7763:
Terahertz Emitters, Receivers, and Applications
Jean-François Lampin; Didier J. Decoster; Manijeh Razeghi, Editor(s)

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