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Proceedings Paper

A multichannel fiber optic photoluminescence system for multiplex biosensor arrays
Author(s): Zhangjing Yi; Zhong Zhong; Kenneth F. Reardon; Weina Wang; Manasi Katragadda; Kevin L. Lear
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Paper Abstract

A multi-channel fiber optic photoluminescence system was developed for real time, in situ and continuous quantitative monitoring of chemical parameters in analytes, with the advantages of ease of use and low cost in manufacturing. The system sequentially excites 8 optodes and measures the resulting photoluminescence with a single photomultiplier. The oxygen sensitive phosphorescent dye or pH sensitive fluorescent dye in the optodes transduces the activity of an enzyme genetically engineered to detect a specific chemical species such as a chlorinated ethene. System operation is described and the relative signal is compared to measurements made with single channel system based on a commercial spectrometer.

Paper Details

Date Published: 24 February 2010
PDF: 6 pages
Proc. SPIE 7559, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications X, 75590T (24 February 2010); doi: 10.1117/12.842900
Show Author Affiliations
Zhangjing Yi, Colorado State Univ. (United States)
Zhong Zhong, Colorado State Univ. (United States)
Kenneth F. Reardon, Colorado State Univ. (United States)
Weina Wang, Colorado State Univ. (United States)
Manasi Katragadda, Colorado State Univ. (United States)
Kevin L. Lear, Colorado State Univ. (United States)

Published in SPIE Proceedings Vol. 7559:
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications X
Israel Gannot, Editor(s)

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