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Proceedings Paper

A study on the qualitative morphological features of the muscle and subcutaneous shapes in vivo using Fourier-domain common path OCT
Author(s): Jae-Ho Han; Liu Xuan; Jin U. Kang; Chul-Gyu Song
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Paper Abstract

In this paper, we have demonstrated a polarization sensitive subcutaneous and muscle imaging based on common path optical coherence tomography (CP-OCT) using near infrared source. The axial and lateral resolutions of our PS-OCT system are 9μm and 6μm, respectively. The internal structural information has been extracted by the real-time signal analysis (Fourier Transform) from the modulated spectral intensity depending on the beam and tissue birefringence. Preliminary results using fresh beef and in vivo rat show that we can visualize the birefringence effect of the tissue collagen fibers in the samples for better image contrast and sensitivity for detection of hidden dermal structures. Compared to conventional CP-OCT, our proposed PS-OCT could provide depth-resolved images, which reflect tissue birefringence.

Paper Details

Date Published: 19 February 2010
PDF: 11 pages
Proc. SPIE 7554, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV, 75542H (19 February 2010); doi: 10.1117/12.841923
Show Author Affiliations
Jae-Ho Han, Johns Hopkins Univ. (United States)
Liu Xuan, Johns Hopkins Univ. (United States)
Jin U. Kang, Johns Hopkins Univ. (United States)
Chul-Gyu Song, Johns Hopkins Univ. (United States)
Chonbuk National Univ. (Korea, Republic of)

Published in SPIE Proceedings Vol. 7554:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIV
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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