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Proceedings Paper

Tissue differentiation by diffuse reflectance spectroscopy for automated oral and maxillofacial laser surgery: ex vivo pilot study
Author(s): Azhar Zam; Florian Stelzle; Katja Tangermann-Gerk; Werner Adler; Emeka Nkenke; Michael Schmidt; Alexandre Douplik
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Paper Abstract

Remote laser surgery lacks of haptic feedback during the laser ablation of tissue. Hence, there is a risk of iatrogenic damage or destruction of anatomical structures like nerves or salivary glands. Diffuse reflectance spectroscopy provides a straightforward and simple approach for optical tissue differentiation. We measured diffuse reflectance from seven various tissue types ex vivo. We applied Linear Discriminant Analysis (LDA) to differentiate the seven tissue types and computed the area under the ROC curve (AUC). Special emphasis was taken on the identification of nerves and salivary glands as the most crucial tissue for maxillofacial surgery. The results show a promise for differentiating tissues as guidance for oral and maxillofacial laser surgery by means of diffuse reflectance.

Paper Details

Date Published: 22 February 2010
PDF: 6 pages
Proc. SPIE 7555, Advanced Biomedical and Clinical Diagnostic Systems VIII, 755516 (22 February 2010); doi: 10.1117/12.841674
Show Author Affiliations
Azhar Zam, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Florian Stelzle, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Katja Tangermann-Gerk, Bavarian Laser Ctr. (Germany)
Werner Adler, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Emeka Nkenke, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Michael Schmidt, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)
Bavarian Laser Ctr. (Germany)
Alexandre Douplik, Friedrich-Alexander-Univ. Erlangen-Nuremberg (Germany)

Published in SPIE Proceedings Vol. 7555:
Advanced Biomedical and Clinical Diagnostic Systems VIII
Tuan Vo-Dinh; Warren S. Grundfest M.D.; Anita Mahadevan-Jansen, Editor(s)

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