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Proceedings Paper

Radial basis function strain estimator
Author(s): Marvin M. Doyley; David Manegold; Minh Q. Phan
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Paper Abstract

Elastography is an emerging imaging modality that can visualize breast tumors via their tissue elasticity and strain properties. Computing strain elastograms by taking the first-order derivative of axial displacement images has a limitation, however; this method will amplify displacement measurement errors that, in turn, will degrade the quality of the strain elastograms. To overcome this limitation, we describe a novel spatial-filtering approach that involves fitting dimensionally increasing, multi-resolution radial basis functions (RBFs) to the displacement field. The results of experiments conducted on an elastically heterogeneous phantom revealed three important observations. Firstly, excessive filtering occurred when spatial filtering was performed using a firstorder radial basis function, to the extent that it was not always possible to discern high-contrast elastic inclusions in the resulting strain elastogram. Secondly, artifacts were incurred when spatial filtering was performed using the high-resolution first-order basis function. Thirdly, second-order basis functions improved our ability to discern lesions in strain elastograms, but this was highly dependent on the resolution of the basis function we employed. More specifically, we achieved better visibility using the low-resolution second-order basis functions, and lower visibility using the high-resolution basis functions. It was concluded that the radial-basis-function strain-estimation method performed sufficiently well to warrant more in-depth studies.

Paper Details

Date Published: 27 February 2009
PDF: 9 pages
Proc. SPIE 7262, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, 72621I (27 February 2009); doi: 10.1117/12.817138
Show Author Affiliations
Marvin M. Doyley, Univ. of Rochester (United States)
David Manegold, Dartmouth College (United States)
Minh Q. Phan, Dartmouth College (United States)

Published in SPIE Proceedings Vol. 7262:
Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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