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Proceedings Paper

Enhanced discrimination of calcified and soft arterial plaques using computed tomography with a multi-energy-window photon counting x-ray detector
Author(s): Xiaolan Wang; Jingyan Xu; Katsuyuki Taguchi; Bradley E. Patt; Douglas J. Wagenaar; Eric C Frey
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Paper Abstract

This work aims at discriminating between soft and calcified coronary artery plaques using microCT with a multi-energywindow photon counting X-ray detector (PCXD). We have previously investigated a solid state X-ray detector which has the capability to count individual photons in different energy windows. The data from these energy windows may be treated as multiple simultaneous X-ray acquisitions within non-overlapping energy windows that can provide additional information about tissue differences. In this work, we simulated a photon counting detector with five energy windows. We investigated two approaches for using the energy information provided by this detector. First, we applied energy weighting to the reconstruction from different energy windows to improve the signal-to-noise ratio between calcified and soft plaques. This resulted in a significant improvement in the signal-to-noise ratio. Second, we applied the basis material decomposition method to discriminate coronary artery plaques based on their calcium content. The results were compared with those obtained using dual-kVp material decomposition. We observed significantly improved contrast-tonoise ratios for the PCXD-based approaches.

Paper Details

Date Published: 13 March 2009
PDF: 6 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72583W (13 March 2009); doi: 10.1117/12.813877
Show Author Affiliations
Xiaolan Wang, The Johns Hopkins Univ. (United States)
Jingyan Xu, The Johns Hopkins Univ. (United States)
Katsuyuki Taguchi, The Johns Hopkins Univ. (United States)
Bradley E. Patt, Gamma Medica-Ideas, Inc. (United States)
Douglas J. Wagenaar, Gamma Medica-Ideas, Inc. (United States)
Eric C Frey, The Johns Hopkins Univ. (United States)

Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)

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