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Proceedings Paper

High temporal resolution cardiac cone-beam CT using a slowly rotating C-arm gantry
Author(s): Guang-Hong Chen; Jie Tang; Brian Nett; Shuai Leng; Joseph Zambelli; Zhihua Qi; Nick Bevins; Scott Reeder; Howard Rowley
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Paper Abstract

Purpose: To achieve three dimensional isotropic dynamic cardiac CT imaging with high temporal resolution for evaluation of cardiac function with a slowly rotating C-arm system. Method and Materials: A recently introduced extension to compressed sensing, viz. Prior Image Constrained Compressed Sensing (PICCS), in which a prior image is used as a constraint in the reconstruction has enabled this application. An in-vivo animal experiment (e.g. a beagle model) was conducted using an interventional C-arm system. The imaging protocol was as follows: contrast was injected, the contrast equilibrated, breathing was suspended for ~14 seconds during which time 420 equally spaced projections were acquired. This data set was used to reconstruct a fully sampled blurred image volume using the conventional FDK algorithm (e.g. the prior image). Then the data set was retrospectively gated into 19 phases according to the recorded ECG signal (heart rate ~ 95bpm) and images were reconstructed with the PICCS algorithm. Results: Cardiac MR was used as the gold standard due to its high temporal resolution. The same short-axis slice was selected from the PICCS-CT data set and the MR data set. Manual contouring on the peak systolic and peak diastolic frames was performed to assess the ejection fraction contribution from this single plane. The calculated ejection fractions with PICCS-CT agreed well with the MR results. Conclusion: We have demonstrated the ability to use a slowly rotating interventional C-arm system in order to make measurements of cardiac function. The new technique provides high isotropic spatial resolution (~0.5 mm) along with high temporal resolution (~ 33 ms). The evaluation of cardiac function demonstrated a great agreement with single slice cardiac MR.

Paper Details

Date Published: 10 March 2009
PDF: 12 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72580C (10 March 2009); doi: 10.1117/12.813810
Show Author Affiliations
Guang-Hong Chen, Univ. of Wisconsin, Madison (United States)
Jie Tang, Univ. of Wisconsin, Madison (United States)
Brian Nett, Univ. of Wisconsin, Madison (United States)
Shuai Leng, Univ. of Wisconsin, Madison (United States)
Joseph Zambelli, Univ. of Wisconsin, Madison (United States)
Zhihua Qi, Univ. of Wisconsin, Madison (United States)
Nick Bevins, Univ. of Wisconsin, Madison (United States)
Scott Reeder, Univ. of Wisconsin, Madison (United States)
Howard Rowley, Univ. of Wisconsin, Madison (United States)

Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)

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