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Proceedings Paper

Microwave imaging utilizing a soft prior constraint
Author(s): Amir H. Golnabi; Paul M. Meaney; Shireen D. Geimer; Margaret W Fanning; Keith D. Paulsen
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Paper Abstract

Microwave imaging for breast cancer detection is becoming a promising alternative technique to current imaging modalities. The significant contrast between dielectric properties of normal and malignant breast tissues makes microwave imaging a useful technique to provide important functional information for diagnoses. However, one of its limitations is that it intrinsically cannot produce high resolution images as other conventional techniques such as MRI or X-ray CT do. Those modalities are capable of producing high quality anatomical images, but unlike microwave imaging, they often cannot provide the necessary functional information about tissue health. In order to refine the resolution of the microwave images while also preserving the functional information, we have recently developed a new strategy, called soft prior regularization. In this new approach, the prior anatomical information of the tissue from either x-ray, MR or other sources is incorporated into our microwave imaging reconstruction algorithm through the following steps: First, the anatomical information is used to create a reconstruction mesh which defines the boundaries of different internal regions. Second, based on location of each mesh node, an associated weighting matrix is defined, such that all nodes within each region are grouped with each other. Finally, the soft prior matrix is used as a regularizing term for our original Gauss- Newton reconstruction algorithm. Results from initial phantom experiments show a significant improvement in the recovered dielectric properties.

Paper Details

Date Published: 27 February 2009
PDF: 10 pages
Proc. SPIE 7262, Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, 72622L (27 February 2009); doi: 10.1117/12.813711
Show Author Affiliations
Amir H. Golnabi, Dartmouth College (United States)
Paul M. Meaney, Dartmouth College (United States)
Shireen D. Geimer, Dartmouth College (United States)
Margaret W Fanning, Dartmouth College (United States)
Keith D. Paulsen, Dartmouth College (United States)

Published in SPIE Proceedings Vol. 7262:
Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging
Xiaoping P. Hu; Anne V. Clough, Editor(s)

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