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Proceedings Paper

Computerized 3D breast phantom with enhanced high-resolution detail
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Paper Abstract

We previously proposed a three-dimensional computerized breast phantom that combines empirical data with the flexibility of mathematical models1. The goal of this project is to enhance the breast phantom to include a more detailed anatomy than currently visible and create additional phantoms from different breast CT data. To improve the level of detail in our existing segmentations, the breast CT data is reconstructed at a higher resolution and additional image processing techniques are used to correct for noise and scatter in the image data. A refined segmentation algorithm is used that incorporates more detail than previously defined. To further enhance high-resolution detail, mathematical models, implementing branching algorithms to extend the glandular tissue throughout the breast and to define Cooper's ligaments, are under investigation. We perform the simulation of mammography and tomosynthesis using an analytical projection algorithm that can be applied directly to the mathematical model of the breast without voxelization2. This method speeds up image acquisition, reduces voxelization artifacts, and produces higher resolution images than the previously used method. The realistic 3D computerized breast phantom will ultimately be incorporated into the 4DXCAT phantom3-5 to be used for breast imaging research.

Paper Details

Date Published: 13 March 2009
PDF: 8 pages
Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72580S (13 March 2009); doi: 10.1117/12.813529
Show Author Affiliations
Christina M. Li, Duke Univ. (United States)
Duke Univ. Medical Ctr. (United States)
W. Paul Segars, Duke Univ. (United States)
Duke Univ. Medical Ctr. (United States)
Joseph Y. Lo, Duke Univ. (United States)
Duke Univ. Medical Ctr. (United States)
Alexander I. Veress, Univ. of Washington (United States)
John M. Boone, Univ. of California, Davis (United States)
James T. Dobbins III, Duke Univ. (United States)
Duke Univ. Medical Ctr. (United States)

Published in SPIE Proceedings Vol. 7258:
Medical Imaging 2009: Physics of Medical Imaging
Ehsan Samei; Jiang Hsieh, Editor(s)

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