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Proceedings Paper

Algorithm for lung cancer detection based on PET/CT images
Author(s): Shinsuke Saita; Keita Ishimatsu; Mitsuru Kubo; Yoshiki Kawata; Noboru Niki; Hideki Ohtsuka; Hiromu Nishitani; Hironobu Ohmatsu; Kenji Eguchi; Masahiro Kaneko; Noriyuki Moriyama
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Paper Abstract

The five year survival rate of the lung cancer is low with about twenty-five percent. In addition it is an obstinate lung cancer wherein three out of four people die within five years. Then, the early stage detection and treatment of the lung cancer are important. Recently, we can obtain CT and PET image at the same time because PET/CT device has been developed. PET/CT is possible for a highly accurate cancer diagnosis because it analyzes quantitative shape information from CT image and FDG distribution from PET image. However, neither benign-malignant classification nor staging intended for lung cancer have been established still enough by using PET/CT images. In this study, we detect lung nodules based on internal organs extracted from CT image, and we also develop algorithm which classifies benignmalignant and metastatic or non metastatic lung cancer using lung structure and FDG distribution(one and two hour after administering FDG). We apply the algorithm to 59 PET/CT images (malignant 43 cases [Ad:31, Sq:9, sm:3], benign 16 cases) and show the effectiveness of this algorithm.

Paper Details

Date Published: 27 February 2009
PDF: 8 pages
Proc. SPIE 7260, Medical Imaging 2009: Computer-Aided Diagnosis, 726034 (27 February 2009); doi: 10.1117/12.812212
Show Author Affiliations
Shinsuke Saita, Univ. of Tokushima (Japan)
Keita Ishimatsu, Univ. of Tokushima (Japan)
Mitsuru Kubo, Univ. of Tokushima (Japan)
Yoshiki Kawata, Univ. of Tokushima (Japan)
Noboru Niki, Univ. of Tokushima (Japan)
Hideki Ohtsuka, Univ. of Tokushima, Graduate School (Japan)
Hiromu Nishitani, Univ. of Tokushima, Graduate School (Japan)
Hironobu Ohmatsu, National Cancer Ctr. Hospital East (Japan)
Kenji Eguchi, Univ. of Teikyo (Japan)
Masahiro Kaneko, National Cancer Ctr. Hospital (Japan)
Noriyuki Moriyama, National Cancer Research Ctr. for Cancer Prevention and Screening (Japan)

Published in SPIE Proceedings Vol. 7260:
Medical Imaging 2009: Computer-Aided Diagnosis
Nico Karssemeijer; Maryellen L. Giger, Editor(s)

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