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Proceedings Paper

Measurement of the local muscular metabolism by time-domain near infrared spectroscopy during knee flex-extension induced by functional electrical stimulation
Author(s): D. Contini; L. Spinelli; A. Torricelli; S. Ferrante; A. Pedrocchi; F. Molteni; G. Ferrigno; R. Cubeddu
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Paper Abstract

We present a preliminary study that combines functional electrical stimulation and time-domain near infrared spectroscopy for a quantitative measurement of the local muscular metabolism during rehabilitation of post-acute stroke patients. Seven healthy subjects and nine post-acute stroke patients underwent a protocol of knee flex-extension of the quadriceps induced by functional electrical stimulation. During the protocol time-domain near infrared spectroscopy measurement were performed on both left and right muscle. Hemodynamic parameters (concentration of oxy- and deoxy-genated hemoglobin) during baseline did not show any significant differences between healthy subject and patients, while functional performances (knee angle amplitude) were distinctly different. Nevertheless, even if their clinical histories were noticeably different, there was no differentiation among functional performances of patients. On the basis of the hemodynamic parameters measured during the recovery phase, instead, it was possible to identify two classes of patients showing a metabolic trend similar or very different to the one obtained by healthy subjects. The presented results suggest that the combination of functional and metabolic information can give an additional tool to the clinicians in the evaluation of the rehabilitation in post-acute stroke patients.

Paper Details

Date Published: 23 February 2009
PDF: 10 pages
Proc. SPIE 7169, Advanced Biomedical and Clinical Diagnostic Systems VII, 71690P (23 February 2009); doi: 10.1117/12.809028
Show Author Affiliations
D. Contini, Politecnico di Milano (Italy)
L. Spinelli, Politecnico di Milano (Italy)
A. Torricelli, Politecnico di Milano (Italy)
S. Ferrante, Politecnico di Milano (Italy)
A. Pedrocchi, Politecnico di Milano (Italy)
F. Molteni, Ospedale Valduce (Italy)
G. Ferrigno, Politecnico di Milano (Italy)
R. Cubeddu, Politecnico di Milano (Italy)

Published in SPIE Proceedings Vol. 7169:
Advanced Biomedical and Clinical Diagnostic Systems VII
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest M.D., Editor(s)

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