
Proceedings Paper
Nonlinear dynamic phase contrast microscopy for microfluidic and microbiological applicationsFormat | Member Price | Non-Member Price |
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Paper Abstract
In live sciences, the observation and analysis of moving living
cells, molecular motors or motion of micro- and nano-objects is a
current field of research. At the same time, microfluidic
innovations are needed for biological and medical applications on
a micro- and nano-scale. Conventional microscopy techniques are
reaching considerable limits with respect to these issues. A
promising approach for this challenge is nonlinear dynamic phase
contrast microscopy. It is an alternative full field approach that
allows to detect motion as well as phase changes of living
unstained micro-objects in real-time, thereby being marker free,
without contact and non destructive, i.e. fully biocompatible. The
generality of this system allows it to be combined with several
other microscope techniques such as conventional bright field or
fluorescence microscopy. In this article we will present the
dynamic phase contrast technique and its applications in analysis
of micro organismic dynamics, micro flow velocimetry and
micro-mixing analysis.
Paper Details
Date Published: 29 August 2008
PDF: 9 pages
Proc. SPIE 7038, Optical Trapping and Optical Micromanipulation V, 70380X (29 August 2008); doi: 10.1117/12.801501
Published in SPIE Proceedings Vol. 7038:
Optical Trapping and Optical Micromanipulation V
Kishan Dholakia; Gabriel C. Spalding, Editor(s)
PDF: 9 pages
Proc. SPIE 7038, Optical Trapping and Optical Micromanipulation V, 70380X (29 August 2008); doi: 10.1117/12.801501
Show Author Affiliations
M. Woerdemann, Westfälische Wilhelms-Univ. (Germany)
M. Oevermann, Westfälische Wilhelms-Univ. (Germany)
M. Oevermann, Westfälische Wilhelms-Univ. (Germany)
Published in SPIE Proceedings Vol. 7038:
Optical Trapping and Optical Micromanipulation V
Kishan Dholakia; Gabriel C. Spalding, Editor(s)
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