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Proceedings Paper

Time-domain fluorescence mammography using early time-reflected signals: finite element approach
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Paper Abstract

Optical spectroscopy based on the use of fluorescent contrast agents has become an interesting tool to detect and localize diseased tissues from healthy structures in a harmless way. Herein, we present a numerical model based on the finite element method that allows to simulate time-resolved reflectance signals from a realistic compartmented two-dimensional model of a breast bearing a small-sized fluorescent inclusion. Results show that the depth location of the inclusion can be well inferred from the observation of the time to reach the half maximum intensity of the reflected signals. Improvements may be obtained if depth localization is provided by a dimensionless indicator based on a twoway reflectance determination.

Paper Details

Date Published: 18 April 2008
PDF: 11 pages
Proc. SPIE 6994, Photon Management III, 69940D (18 April 2008); doi: 10.1117/12.781622
Show Author Affiliations
Jean-Pierre L'Huillier, Arts et Métiers ParisTech (France)

Published in SPIE Proceedings Vol. 6994:
Photon Management III
John T. Sheridan; Frank Wyrowski, Editor(s)

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