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Proceedings Paper

Versatile confocal/optical coherence tomography system for embryonic developmental imaging
Author(s): A. Bradu; Lisha Ma; J. Bloor; A. Podoleanu
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Paper Abstract

An Optical Coherence Tomography (OCT) imaging system has been designed and constructed to acquire images of scattering biological samples. By simultaneously acquiring and displaying high resolution en-face (C-scan) OCT and Laser Scanning Confocal images of Drosophila melanogaster embryos we demonstrate the potential of the system to be used as a powerful tool for imaging in Drosophila embryonic development. The system can equally be used for non invasive visualizations and measurements of the movement of Drosophila melanogaster larval heart and can easily be switched in the OCT B-scan regime. The confocal channel adds guidance as the specimen can be quickly located and this makes the use of the system in a large scale gene screen feasible.

Paper Details

Date Published: 18 February 2008
PDF: 6 pages
Proc. SPIE 6847, Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII, 68471W (18 February 2008); doi: 10.1117/12.765824
Show Author Affiliations
A. Bradu, Univ. of Kent (United Kingdom)
Lisha Ma, Univ. of Kent (United Kingdom)
J. Bloor, Univ. of Kent (United Kingdom)
A. Podoleanu, Univ. of Kent (United Kingdom)

Published in SPIE Proceedings Vol. 6847:
Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII
Joseph A. Izatt; James G. Fujimoto; Valery V. Tuchin, Editor(s)

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