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Proceedings Paper

The correlation study of temperature distribution with the immunology response under laser radiation
Author(s): Yichao Chen; Robert E. Nordquist; Mark F. Naylor; Feng Wu; Hong Liu; Yasvir A. Tesiram; Andrew Abbott; Rheal A. Towner; Wei R. Chen
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Paper Abstract

The 3-D, in vivo temperature distributions within tumor-bearing rats were measured using Magnetic Resonance Imaging (MRI) technique. The in vivo thermal distributions of rats were measured using MRI chemical shift of water proton density. DMBA-4 tumor bearing rats are treated using laser photothermal therapy combined with immunoadjuvant under the observation of MRI. The thermal images and the immunological responses were studied and their relationships were investigated. The study of thermal distribution and correlation with the immunological response under laser treatment provided rich information with potential guidance for thermal-immunological therapy.

Paper Details

Date Published: 28 February 2008
PDF: 7 pages
Proc. SPIE 6857, Biophotonics and Immune Responses III, 68570E (28 February 2008); doi: 10.1117/12.763964
Show Author Affiliations
Yichao Chen, Univ. of Central Oklahoma (United States)
Robert E. Nordquist, Wound Healing of Oklahoma (United States)
Mark F. Naylor, Univ. of Oklahoma College of Medicine (United States)
Feng Wu, Chongqing Medical Univ. (China)
Hong Liu, Univ. of Oklahoma (United States)
Yasvir A. Tesiram, Oklahoma Medical Research Foundation (United States)
Andrew Abbott, Oklahoma Medical Research Foundation (United States)
Rheal A. Towner, Oklahoma Medical Research Foundation (United States)
Wei R. Chen, Univ. of Central Oklahoma (United States)

Published in SPIE Proceedings Vol. 6857:
Biophotonics and Immune Responses III
Wei R. Chen, Editor(s)

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