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Proceedings Paper

Imaging the anterior eye segment by polarization-sensitive spectral-domain and swept-source optical coherence tomography
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Paper Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) has been developed to measure the birefringent properties of the human eye. In the retina, retinal nerve fiber layer and retinal pigment epitherial layer have the characteristic birefringent properties.1.2 In addition to such normal tissue, abnormal fibrous tissue of the retina can be detected by PS-OCT.3 In the anterior segment, the cornea is a birefringent tissue due to the multi-layered fibril structure.4 The sclera and tendon also have the birefringence and the contrast of these structures can be enhanced by PS-OCT.5 These studies have been used time-domain or spectral-domain PS-OCT. Recently, swept-source OCT (SS-OCT) has been applied for anterior eye segment imaging.6 At the 1.3 um wavelength, SS-OCT is more promising than spectral-domain OCT, because the available camera for the spectrometer is limited. Three-dimensional imaging of the anterior segment is possible owing to the high penetration, high acquisition speed and high sensitivity. We have developed a new system of SS-OCT with polarization sensitivity. In this study, we measure the birefringent properties of anterior eye segment by polarization-sensitive spectral-domain OCT (PS-SD-OCT) at 840 nm and polarizationsensitive swept-source OCT (PS-SS-OCT) at 1.3 um, and evaluated the possibilities for clinical application.

Paper Details

Date Published: 25 February 2008
PDF: 5 pages
Proc. SPIE 6844, Ophthalmic Technologies XVIII, 68441C (25 February 2008); doi: 10.1117/12.761590
Show Author Affiliations
Masahiro Miura, Tokyo Medical Univ. (Japan)
Univ. of Tsukuba (Japan)
Masahiro Yamanari, Univ. of Tsukuba (Japan)
Toyohiko Yatagai, Univ. of Tsukuba (Japan)
Yoshiaki Yasuno, Univ. of Tsukuba (Japan)

Published in SPIE Proceedings Vol. 6844:
Ophthalmic Technologies XVIII
Bruce E. Stuck; Fabrice Manns; Per G. Söderberg; Michael Belkin M.D.; Arthur Ho, Editor(s)

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