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Proceedings Paper

Analysis of inserts in prokaryote genomes
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Paper Abstract

Nucleotide genomic signals satisfy regularities that reveal restrictions in the distribution of nucleotides and pairs of nucleotides along DNA sequences. Structurally, a chromosome appears to be more than a plain text, by satisfying symmetry constrains that evoke the rhythm and rhyme in poems. These regularities make it easy to identify exogenous inserts in the genomes of prokaryotes, because such inserts obey different regularities than the background sequence. The paper presents instances of inserts found in the genomes of Bacillus subtilis, Mycobacterium tuberculosis and other prokaryotes. Inserts of exogenous material are frequently accompanied by complementary inserts tending to restore the original constrains.

Paper Details

Date Published: 29 February 2008
PDF: 9 pages
Proc. SPIE 6859, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VI, 68591D (29 February 2008); doi: 10.1117/12.761004
Show Author Affiliations
Paul Dan Cristea, Polytechnical Univ. of Bucharest (Romania)
Vrije Univ. Brussel (Belgium)
Rodica Aurora Tuduce, Polytechnical Univ. of Bucharest (Romania)

Published in SPIE Proceedings Vol. 6859:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues VI
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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