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Proceedings Paper

Full path Monte Carlo simulation of fluorescence in non-voxelized complex heterogeneous mouse model
Author(s): Jean-Francois Delorme; Guobin Ma; Frederic Lesage; Frederic Leblond; Anader Benyamin-Seyar
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Paper Abstract

In this article we propose an approach to improve the Monte Carlo simulation accuracy by implementing a full photon path integration simulation in a non-voxelized complex three-dimensional heterogeneous model. Mouse body shape, organs optical heterogeneities and fluorophore distribution are simulated by using boundary surface elements and basic analytical shapes. In addition, external and internal surface roughness and refractive index mismatch for complex angular objects are also considered and results are briefly compared with time sampled space voxelized Monte Carlo code, in order to illustrate the impact of these improvements on the simulation results.

Paper Details

Date Published: 20 February 2008
PDF: 12 pages
Proc. SPIE 6854, Optical Interactions with Tissue and Cells XIX, 68541M (20 February 2008); doi: 10.1117/12.760822
Show Author Affiliations
Jean-Francois Delorme, Advanced Research Technologies (Canada)
Guobin Ma, Advanced Research Technologies (Canada)
Frederic Lesage, Ecole Polytechnique de Montreal (Canada)
Frederic Leblond, Advanced Research Technologies (Canada)
Anader Benyamin-Seyar, Advanced Research Technologies (Canada)

Published in SPIE Proceedings Vol. 6854:
Optical Interactions with Tissue and Cells XIX
Steven L. Jacques; William P. Roach; Robert J. Thomas, Editor(s)

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