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Proceedings Paper

Fluorescence optical tomography with a priori information
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Paper Abstract

In this work, we discuss the incorporation of a priori information into the inverse problem formulation for fluorescence optical tomography. In this respect, we first formulate the inverse problem in the optimization framework which allows the incorporation of a priori information about the solution and its gradient. Then, we consider the variational problem, which is equivalent to the optimization problem and prove the existence and uniqueness of the solution. Finally, we discuss the design of the functions that incorporate the a priori information into the inverse problem formulation and present a model problem to illustrate the design procedure.

Paper Details

Date Published: 14 February 2007
PDF: 15 pages
Proc. SPIE 6431, Multimodal Biomedical Imaging II, 643107 (14 February 2007); doi: 10.1117/12.715073
Show Author Affiliations
Murat Guven, Rensselaer Polytechnic Institute (United States)
Birsen Yazici, Rensselaer Polytechnic Institute (United States)
Vasilis Ntziachristos, Harvard Medical School (United States)

Published in SPIE Proceedings Vol. 6431:
Multimodal Biomedical Imaging II
Fred S. Azar, Editor(s)

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