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Proceedings Paper

A scaling Monte Carlo method for diffuse reflectance computation from multi-layered media
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Paper Abstract

A scaling Monte Carlo method has been developed to quickly calculate diffuse reflectance spectra from multi-layered media for a wide range of optical properties. This method employs the photon trajectory information generated from a single baseline Monte Carlo simulation for a homogeneous medium to scale the exit distance and exit weight of photons for the new optical properties in multi-layered media. The method was tested for simulating diffuse reflectance from both a two-layered and a three-layered epithelial tissue model when using a flat-tip fiber-optic probe with variable source-detector separations. The scaling method can reduce computation time by more than two orders of magnitude compared to independent Monte Carlo simulations. This scaling method is particularly suited to simulating diffuse reflectance spectra or creating a Monte Carlo database to extract optical properties of layered media, which may potentially help spread the use of Monte Carlo modeling in the spectroscopy research of layered tissues.

Paper Details

Date Published: 6 February 2007
PDF: 12 pages
Proc. SPIE 6435, Optical Interactions with Tissue and Cells XVIII, 643509 (6 February 2007); doi: 10.1117/12.708574
Show Author Affiliations
Quan Liu, Duke Univ. (United States)
Nirmala Ramanujam, Duke Univ. (United States)

Published in SPIE Proceedings Vol. 6435:
Optical Interactions with Tissue and Cells XVIII
Steven L. Jacques; William P. Roach, Editor(s)

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