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Proceedings Paper

Optimal probe design for dual-modality breast imaging
Author(s): Chen Xu; Quing Zhu
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Paper Abstract

Shallow breast lesions less than 1.0 cm deep are frequently seen in patients when they are scanned in a supine position by a hand-held combined ultrasound and optical probe. Reflection boundary condition is suitable for imaging shallow lesions, but it is not sensitive enough for imaging lesions deeper than 1.0 cm. The absorption boundary condition is more desirable for imaging deeper lesions. However, it is less sensitive to shallower lesions unless the optical sources are positioned right on top of the lesion which is unknown in general. To solve this problem, we have designed a new probe which incorporates three angled sources to improve the illumination of the shallow region underneath the co-registered ultrasound probe. Monte Carlo method is extended to include an absorber in the medium and used to evaluate the analytical results. Simulations have shown that the combination of tilted and peripherally located sources can improve reconstruction compared with the probe with no tilted sources. Phantom experiments agree with simulation results.

Paper Details

Date Published: 13 February 2007
PDF: 9 pages
Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 64340B (13 February 2007); doi: 10.1117/12.702218
Show Author Affiliations
Chen Xu, Univ. of Connecticut (United States)
Quing Zhu, Univ. of Connecticut (United States)

Published in SPIE Proceedings Vol. 6434:
Optical Tomography and Spectroscopy of Tissue VII
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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