Share Email Print

Proceedings Paper

Prior information in fluorescence molecular tomography based on multispectral fluorescence emission
Format Member Price Non-Member Price
PDF $17.00 $21.00

Paper Abstract

Fluorescence molecular tomography (FMT) suffers from inherent ill-posedness due to the vast number of possible solutions to the reconstruction problem. To increase the robustness of such a problem one need prior information. We present here a method for rendering a priori information of the position of a fluorescent inclusion inside turbid media. The method utilizes solely two spectral bands within the fluorescence spectrum emitted from the fluorophore. The method is presented and verified using experimental data from a tissue phantom. The confinement is also used to impose weights onto the voxels before the inversion of the linear set of equations describing the FMT problem.

Paper Details

Date Published: 13 February 2007
PDF: 9 pages
Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 64340D (13 February 2007); doi: 10.1117/12.699464
Show Author Affiliations
J. Axelsson, Lund Univ. (Sweden)
J. Svensson, Lund Univ. (Sweden)
S. Andersson-Engels, Lund Univ. (Sweden)

Published in SPIE Proceedings Vol. 6434:
Optical Tomography and Spectroscopy of Tissue VII
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

© SPIE. Terms of Use
Back to Top
Sign in to read the full article
Create a free SPIE account to get access to
premium articles and original research
Forgot your username?