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Proceedings Paper

Dual wavelength approach for the estimation of the relative concentration of two absorbers: Monte Carlo simulations
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Paper Abstract

We describe a Monte Carlo test of a new method for the calculation of the relative concentrations of two localized absorbers in a highly scattering medium. The method, previously proposed by us, is based on a property of the intensity changes caused by the localized absorbers, which is strictly verified by diffusion theory within first order perturbation, and remains approximately verified beyond the limits of first order perturbation. The applicability of the method was theoretically and experimentally validated in an infinite medium geometry for "small size" perturbations, as well as for larger perturbations. The purpose of the Monte Carlo test reported here is to show that the method is applicable also to a slab geometry for a relatively large (both in size and optical contrast) perturbation. This test indicates that the dual wavelength approach to the estimation of the relative concentration of two absorbers can be insensitive to the medium geometry as well as the size and geometry of the localized inclusion.

Paper Details

Date Published: 13 February 2007
PDF: 5 pages
Proc. SPIE 6434, Optical Tomography and Spectroscopy of Tissue VII, 643412 (13 February 2007); doi: 10.1117/12.698749
Show Author Affiliations
Angelo Sassaroli, Tufts Univ. (United States)
Ning Liu, Tufts Univ. (United States)
Sergio Fantini, Tufts Univ. (United States)

Published in SPIE Proceedings Vol. 6434:
Optical Tomography and Spectroscopy of Tissue VII
Britton Chance; Robert R. Alfano; Bruce J. Tromberg; Mamoru Tamura; Eva Marie Sevick-Muraca, Editor(s)

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