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Proceedings Paper

Novel concepts of vertical-cavity laser-based optical traps for biomedical applications
Author(s): Andrea Kroner; Johanna F. May; Ihab Kardosh; Fernando Rinaldi; Hendrik Roscher; Rainer Michalzik
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Paper Abstract

Using vertical-cavity surface-emitting lasers (VCSELs) as light sources in optical traps offers various advantages compared to the common approaches. In particular, these are small dimensions, a circularly symmetric output beam, and the simple fabrication of two-dimensional laser arrays. We investigate the application of VCSELs in a standard tweezers setup, where trapping forces of up to 4.4 pN are achieved with 15 μm polystyrene particles and a transverse multi-mode VCSEL. The latter has improved trapping characteristics compared to a single-mode device. By introducing a small-spaced array of three VCSELs in the setup, non-mechanical movement with average velocities of up to 3 μm/s is demonstrated with 10 μm particles. Furthermore, the novel concept of the integrated optical trap is presented. By integrating a microlens directly on the VCSEL output facet, two-dimensional optical trapping is achieved in a small-sized system without any external optics. Elevation and trapping of 10 μm polystyrene particles is demonstrated at optical output powers of about 5 mW. In order to improve the beam quality of the lasers, the inverted surface relief technique is applied, which eliminates a previously observed offset between laser center and trapped particle.

Paper Details

Date Published: 14 April 2006
PDF: 12 pages
Proc. SPIE 6191, Biophotonics and New Therapy Frontiers, 619112 (14 April 2006); doi: 10.1117/12.662458
Show Author Affiliations
Andrea Kroner, Ulm Univ. (Germany)
Johanna F. May, Ulm Univ. (Germany)
Ihab Kardosh, Ulm Univ. (Germany)
Fernando Rinaldi, Ulm Univ. (Germany)
Hendrik Roscher, Ulm Univ. (Germany)
Rainer Michalzik, Ulm Univ. (Germany)


Published in SPIE Proceedings Vol. 6191:
Biophotonics and New Therapy Frontiers
Romualda Grzymala; Olivier Haeberle, Editor(s)

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