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Proceedings Paper

Role of speckles in laser Doppler perfusion imaging: an investigation on particle suspensions
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Paper Abstract

We show that speckles play an important role in laser Doppler perfusion imaging. The influence of speckles on the signal amplitude and the Doppler spectrum is demonstrated experimentally on particle suspensions with different scattering levels and varying beam width. Polystyrene microsphere suspensions with known optical properties are used to make scattering samples. A theoretical model is explained to calculate the speckle size from the back scattered intensity distributions. The coherence area is calculated with Monte Carlo simulations on different scattering samples and experiments are performed to validate our theoretical model. The experimental results are in good agreement with our theoretical predictions.

Paper Details

Date Published: 14 April 2006
PDF: 8 pages
Proc. SPIE 6191, Biophotonics and New Therapy Frontiers, 619113 (14 April 2006); doi: 10.1117/12.661601
Show Author Affiliations
Vinayakrishnan Rajan, Univ. of Twente (Netherlands)
Babu Varghese, Univ. of Twente (Netherlands)
Ton G. van Leeuwen, Univ. of Twente (Netherlands)
Wiendelt Steenbergen, Univ. of Twente (Netherlands)

Published in SPIE Proceedings Vol. 6191:
Biophotonics and New Therapy Frontiers
Romualda Grzymala; Olivier Haeberle, Editor(s)

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