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Proceedings Paper

Shortest path adjusted similarity metrics for resolving boundary perturbations in scaffold images for tissue engineering
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Paper Abstract

The degree of match between the delineation result produced by a segmentation technique and the ground truth can be assessed using robust "presence-absence" resemblance measures. Previously, we had investigated and introduced an exhaustive list of similarity indices for assessing multiple segmentation techniques. However, these measures are highly sensitive to even minor boundary perturbations which imminently manifest in the segmentations of random biphasic spaces reminiscent of the stochastic pore-solid distributions in the tissue engineering scaffolds. This paper investigates the ideas adapted from ecology to emphasize global resemblances and ignore minor local dissimilarities. It uses concepts from graph theory to perform controlled local mutations in order to maximize the similarities. The effect of this adjustment is investigated on a comprehensive list (forty nine) of similarity indices sensitive to the over- and under- estimation errors associated with image delineation tasks.

Paper Details

Date Published: 15 March 2006
PDF: 12 pages
Proc. SPIE 6144, Medical Imaging 2006: Image Processing, 61444E (15 March 2006); doi: 10.1117/12.654000
Show Author Affiliations
Srinivasan Rajagopalan, Mayo Clinic College of Medicine (United States)
Richard Robb, Mayo Clinic College of Medicine (United States)

Published in SPIE Proceedings Vol. 6144:
Medical Imaging 2006: Image Processing
Joseph M. Reinhardt; Josien P. W. Pluim, Editor(s)

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