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Proceedings Paper

Patient-specific models of wall stress in abdominal aortic aneurysm: a comparison between MR and CT
Author(s): Sander de Putter; Marcel Breeuwer; Frans N. van de Vosse; Ursula Kose; Frans A. Gerritsen
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Paper Abstract

Finite element method based patient-specific wall stress in abdominal aortic aneurysm (AAA) may provide a more accurate rupture risk predictor than the currently used maximum transverse diameter. In this study, we have investigated the sensitivity of the wall stress in AAA with respect to geometrical variations. We have acquired MR and CT images for four patients with AAA. Three individual users have delineated the AAA vessel wall contours on the image slices. These contours were used to generate synthetic feature images for a deformable model based segmentation method. We investigated the reproducibility and the influence of the user variability on the wall stress. For sufficiently smooth models of the AAA wall, the peak wall stress is reproducible for three out of the four AAA geometries. The 0.99 percentiles of the wall stress show excellent reproducibility for all four AAAs. The variations induced by user variability are larger than the errors caused by the segmentation variability. The influence of the user variability appears to be similar for MR and CT. We conclude that the peak wall stress in AAA is sensitive to small geometrical variations. To increase reproducibility it appears to be best not to allow too much geometrical detail in the simulations. This could be achieved either by using a sufficiently smooth geometry representation or by using a more robust statistical parameter derived from the wall stress distribution.

Paper Details

Date Published: 13 March 2006
PDF: 12 pages
Proc. SPIE 6143, Medical Imaging 2006: Physiology, Function, and Structure from Medical Images, 61430D (13 March 2006); doi: 10.1117/12.651675
Show Author Affiliations
Sander de Putter, Technische Univ. Eindhoven (Netherlands)
Marcel Breeuwer, Philips Medical Systems (Netherlands)
Frans N. van de Vosse, Technische Univ. Eindhoven (Netherlands)
Ursula Kose, Philips Medical Systems (Netherlands)
Frans A. Gerritsen, Technische Univ. Eindhoven (Netherlands)
Philips Medical Systems (Netherlands)

Published in SPIE Proceedings Vol. 6143:
Medical Imaging 2006: Physiology, Function, and Structure from Medical Images
Armando Manduca; Amir A. Amini, Editor(s)

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