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Proceedings Paper

Clinical feasibility of various optical instruments for quantitative evaluation of pulsed-dye laser treatment of port wine stain skin
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Paper Abstract

For quantitative prediction and evaluation of pulsed dye laser therapy of port wine stain (PWS) skin, the CIE L*a*b* color difference, ΔE*, has been utilized to characterize numerically the color differences between normal untreated and treated PWS skin. Three optical instruments (Minolta chromameter CR-200, a cross-polarized diffuse reflectance imaging system, and visual reflectance spectrometers) are compared to investigate their clinical feasibility for quantitative color assessment. Compared to the chromameter as a standard measurement instrument, other instruments also provide valuable measurements of skin color for the relative quantification of PWS treatment outcome. The fiber-optic visual reflectance spectrometer is preferable for continuous measurement of a small area of skin. The cross-polarized imaging system is useful as a simple non-contact measurement technique to provide spatially resolved color difference images.

Paper Details

Date Published: 25 April 2005
PDF: 7 pages
Proc. SPIE 5686, Photonic Therapeutics and Diagnostics, (25 April 2005); doi: 10.1117/12.589706
Show Author Affiliations
Chang-Seok Kim, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)
Byungjo Jung, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)
Bernard Choi, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)
Wim Verkruysse, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)
Rong Zhang, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)
John Stuart Nelson, Beckman Laser Institute and Medical Clinic, Univ. of California/Irvine (United States)


Published in SPIE Proceedings Vol. 5686:
Photonic Therapeutics and Diagnostics
Brian Jet-Fei Wong M.D.; Eugene A. Trowers M.D.; Kenton W. Gregory M.D.; Abraham Katzir; Nikiforos Kollias; Reza S. Malek M.D.; Henry Hirschberg M.D.; Kenneth Eugene Bartels D.V.M.; Steen J. Madsen; Lloyd P. Tate V.D.M.; Lawrence S. Bass M.D.; Werner T. W. de Riese; Karen M. McNally-Heintzelman, Editor(s)

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