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Proceedings Paper

Sinogram interpolation for sparse-view micro-CT with deep learning neural network
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Paper Abstract

In sparse-view Computed Tomography (CT), only a small number of projection images are taken around the object, and sinogram interpolation method has a significant impact on final image quality. When the amount of sparsity - the amount of missing views in sinogram data – is not high, conventional interpolation methods have yielded good results. When the amount of sparsity is high, more advanced sinogram interpolation methods are needed. Recently, several deep learning (DL) based sinogram interpolation methods have been proposed. However, those DL-based methods have mostly tested so far on computer simulated sinogram data rather experimentally acquired sinogram data. In this study, we developed a sinogram interpolation method for sparse-view micro-CT based on the combination of U-Net and residual learning. We applied the method to sinogram data obtained from sparse-view micro-CT experiments, where the sparsity reached 90%. The interpolated sinogram by the DL neural network was fed to FBP algorithm for reconstruction. The result shows that both RMSE and SSIM of CT image are greatly improved. The experimental results demonstrate that this sinogram interpolation method produce significantly better results over standard linear interpolation methods when the sinogram data are extremely sparse.

Paper Details

Date Published: 1 March 2019
PDF: 7 pages
Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109482O (1 March 2019); doi: 10.1117/12.2512979
Show Author Affiliations
Xu Dong, Virginia Polytechnic Institute and State Univ. (United States)
Swapnil Vekhande, Virginia Polytechnic Institute and State Univ. (United States)
Guohua Cao, Virginia Polytechnic Institute and State Univ. (United States)

Published in SPIE Proceedings Vol. 10948:
Medical Imaging 2019: Physics of Medical Imaging
Taly Gilat Schmidt; Guang-Hong Chen; Hilde Bosmans, Editor(s)

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