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Proceedings Paper

Laboratory-based x-ray phase contrast CT technology for clinical intra-operative specimen imaging
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Paper Abstract

The design of an X-ray phase contrast tomography system for intra-operative specimen imaging based on edge illumination is presented. The use of edge illumination makes possible working with large focus, polychromatic X-ray sources reducing acquisition times of tomography scans down to values compatible with clinical use, while maintaining phase sensitivity in a compact device. The results collected so far show that application of this technology to breast conservation surgery has great potential to reduce re-operations, thus saving additional costs for healthcare services and stress for patients.

Paper Details

Date Published: 1 March 2019
PDF: 10 pages
Proc. SPIE 10948, Medical Imaging 2019: Physics of Medical Imaging, 109481R (1 March 2019); doi: 10.1117/12.2511770
Show Author Affiliations
Lorenzo Massimi, Univ. College London (United Kingdom)
Charlotte K. Hagen, Univ. College London (United Kingdom)
Marco Endrizzi, Univ. College London (United Kingdom)
Peter R. T. Munro, Univ. College London (United Kingdom)
Glafkos Havariyoun, Univ. College London (United Kingdom)
P. M. Sam Hawker, Nikon, X-Tek Systems Ltd. (United Kingdom)
Bennie Smit, Nikon, X-Tek Systems Ltd. (United Kingdom)
Alberto Astolfo, Nikon, X-Tek Systems Ltd. (United Kingdom)
Oliver J. Larkin, Nikon, X-Tek Systems Ltd. (United Kingdom)
Richard M. Waltham, Nikon, X-Tek Systems Ltd. (United Kingdom)
Zoheb Shah, Queen Mary Univ. of London (United Kingdom)
Stephen W. Duffy, Queen Mary Univ. of London (United Kingdom)
Rachel L. Nelan, Queen Mary Univ. of London (United Kingdom)
Anthony Peel, St. Bartholomew's Hospital (United Kingdom)
Tamara Suaris, St. Bartholomew's Hospital (United Kingdom)
J. Louise Jones, Queen Mary Univ. of London (United Kingdom)
St. Bartholomew's Hospital (United Kingdom)
Ian G. Haig, Nikon, X-Tek Systems Ltd. (United Kingdom)
Alessandro Olivo, Queen Mary Univ. of London (United Kingdom)


Published in SPIE Proceedings Vol. 10948:
Medical Imaging 2019: Physics of Medical Imaging
Taly Gilat Schmidt; Guang-Hong Chen; Hilde Bosmans, Editor(s)

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