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Proceedings Paper

Modeling the load resistance in laser-assisted cornea transplantation
Author(s): Francesca Rossi; Paolo Ferrara; Michele Rossi; Roberto Pini; Alex Malandrini; Annalisa Canovetti; Luca Menabuoni
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Paper Abstract

In femtosecond laser assisted keratoplasty different surgical wound profiles can be performed, such as mushroom, zigzag, anvil, Christmas tree, etc. The cut shape is chosen by the surgeon on the basis of patient’s morphology and pathology and on the gained experience. This work aims to qualitatively evaluate the biomechanical load resistance of the different configurations that are currently used in penetrating keratoplasty (PK), in order to support the surgeon’s choice. A 2D and a 3D finite-element biomechanical model of the human cornea was developed and different geometric configurations for PK were designed. The internal pressure was raised until the wound misaligned; wound prolapse then occurred. As a result, we evidenced a different wound resistance to internal loads in the different laser trephined profiles. The anvil profile was more resistant to the increasing internal pressure than was the mushroom or the zig zag pattern. This result is in accordance with the clinical results observed in previously treated patients. The anvil profile enabled the apposition of a restricted number of sutures and early suture removal, thanks to its greater mechanical load resistance. These advantages can contribute to a faster visual recovery in patients undergoing penetrating keratoplasty.

Paper Details

Date Published: 28 February 2019
PDF: 5 pages
Proc. SPIE 10858, Ophthalmic Technologies XXIX, 1085826 (28 February 2019); doi: 10.1117/12.2509683
Show Author Affiliations
Francesca Rossi, Istituto di Fisica Applicata, CNR (Italy)
Paolo Ferrara, National Institute of Optics. National Research Council (Italy)
Michele Rossi, Istituto di Fisica Applicata, CNR (Italy)
Roberto Pini, Istituto di Fisica Applicata, CNR (Italy)
Alex Malandrini, Nuovo Ospedale S. Stefano (Italy)
Annalisa Canovetti, Nuovo Ospedale S. Stefano (Italy)
Luca Menabuoni, Nuovo Ospedale S. Stefano (Italy)

Published in SPIE Proceedings Vol. 10858:
Ophthalmic Technologies XXIX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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