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Proceedings Paper

Lacrimal canaliculus imaging by dynamic OCT using extrinsic contrast agent
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Paper Abstract

In this study, the human lacrimal canaliculus (LC), an important segment of the lacrimal drainage system, was imaged using dynamic optical coherence tomography (D-OCT) and the 3D structure of the LC was rendered. In D-OCT system, a turbid commercial ophthalmic solution was used as an extrinsic contrast agent. The lumen boundary of the LC appeared clearer in D-OCT images compared with simple static OCT images, making segmentation easier. D-OCT was performed by calculating the sum of the squared differences of intensities with two different normalization parameters. By color-combining these two D-OCT images and static OCT image, using image calculation software, the contrast agent and the lumen boundary can be clearly separated. 3D volumetric images of the LCs are demonstrated.

Paper Details

Date Published: 28 February 2019
PDF: 6 pages
Proc. SPIE 10858, Ophthalmic Technologies XXIX, 108581H (28 February 2019); doi: 10.1117/12.2508137
Show Author Affiliations
Reiko Yoshimura, Kitasato Univ. (Japan)
Dong-hak Choi, Kitasato Univ. (Japan)
Masahiro Fujimoto, Kyoto Univ. (Japan)
Akihito Uji, Kyoto Univ. (Japan)
Fumiko Hiwatashi, Systems Engineering Inc. (Japan)
Kohji Ohbayashi, Systems Engineering Inc. (Japan)
Advanced Imaging Co., Ltd. (Japan)

Published in SPIE Proceedings Vol. 10858:
Ophthalmic Technologies XXIX
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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