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Proceedings Paper

A heuristic algorithm to calculate optical properties of turbid media
Author(s): Marius Hinsberger; Stefan Naumann; Klaus-Uwe Gollmer; Achim Langenbucher; Bernhard Schick; Gentiana Wenzel M.D.
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Paper Abstract

The interaction between biological tissues and light of a certain wavelength is influenced by the optical properties of each tissue. These are typically estimated from of the measurements of the main characteristics of the radiations pathway.

We herein present our approach that uses a customized version of the Monte Carlo Multi-Layer Algorithm (MCML)1 to simulate the radiation propagation through biological tissues. We assumed a set of optical properties for each tissue and simulated the above mentioned measurements in silico. A comparison was then done between the results of the simulation and the results of real measurements.2 Further, an optimization algorithm searched the set of optical properties that best fit the real optical properties of each tissue. This algorithm was based on adaptions of the Monte-Carlo Simulated Annealing algorithm3 and the Downhill Simplex algorithm4 We implemented the MCML using NVidias CUDA application programming interface to speed up the optimization procedure. We validated the software by using van de Hulsts table for Henyey-Greenstein scattering.2 A linear regression resulted in coefficients of determination between 0.929 and 0.973 for the optical properties. Our results prove that our algorithm can be effectively used for the determination of the optical properties of turbid media.

One first application for this software is the support in the development of a new generation of hearing devices based on optical energy.

Paper Details

Date Published: 17 May 2018
PDF: 6 pages
Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 106853O (17 May 2018); doi: 10.1117/12.2306778
Show Author Affiliations
Marius Hinsberger, Univ. des Saarlandes (Germany)
Stefan Naumann, Hochschule Trier (Germany)
Klaus-Uwe Gollmer, Hochschule Trier (Germany)
Achim Langenbucher, Univ. des Saarlandes (Germany)
Bernhard Schick, Univ. des Saarlandes (Germany)
Gentiana Wenzel M.D., Univ. des Saarlandes (Germany)

Published in SPIE Proceedings Vol. 10685:
Biophotonics: Photonic Solutions for Better Health Care VI
Jürgen Popp; Valery V. Tuchin; Francesco Saverio Pavone, Editor(s)

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