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Proceedings Paper

Optical properties of colorectal muscle in visible/NIR range
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Paper Abstract

Knowledge of the optical properties of tissues is necessary, since they change from tissue to tissue and can differ between normal and pathological conditions. These properties are used in light transport models with various areas of application. In general, tissues have significantly high scattering coefficient when compared to the absorption coefficient and such difference usually increases with decreasing wavelength. The study of the wavelength dependence of the optical properties has been already made for several animal and human tissues, but extensive research is still needed in this field. Considering that most of the Biophotonics techniques used in research and clinical practice use visible to NIR light, we have estimated the optical properties of colorectal muscle (muscularis propria) between 400 and 1000 nm. The samples used were collected from patients undergoing resection surgery for colorectal carcinoma. The estimated scattering coefficient for colorectal muscle decreases exponentially with wavelength from 122 cm-1 at 400 nm to 95 cm-1 at 650 nm and to 91 cm-1 at 1000 nm. The absorption coefficient shows a wavelength dependence according to the behavior seen for other tissues, since it decreases from 8 cm-1 at 400 nm to 2.6 cm-1 at 650 nm and to 1.3 cm-1 at 1000 nm. The estimated optical properties differ from the ones that we have previously obtained for normal and pathological colorectal mucosa. The data obtained in this study covers an extended spectral range and it can be used for planning optical clearing treatments for some wavelengths of interest.

Paper Details

Date Published: 17 May 2018
PDF: 12 pages
Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 106853D (17 May 2018); doi: 10.1117/12.2306586
Show Author Affiliations
Isa Carneiro, Instituto Português de Oncologia do Porto FG (Portugal)
Sónia Carvalho, Instituto Português de Oncologia do Porto FG (Portugal)
Rui Henrique, Instituto Português de Oncologia do Porto FG (Portugal)
Univ. do Porto (Portugal)
Luís M. Oliveira, Instituto Superior de Engenharia do Porto (Portugal)
Instituto Politécnico do Porto (Portugal)
Valery V. Tuchin, Saratov State Univ. (Russian Federation)
Precision Mechanics and Control Institute of the Russian Academy of Sciences (Russian Federation)
ITMO Univ. (Russian Federation)

Published in SPIE Proceedings Vol. 10685:
Biophotonics: Photonic Solutions for Better Health Care VI
Jürgen Popp; Valery V. Tuchin; Francesco Saverio Pavone, Editor(s)

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