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Proceedings Paper

Automated registration and stitching of multiple 3D ultrasound images for monitoring neonatal intraventricular hemorrhage
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Paper Abstract

Dilatation of the cerebral ventricles is a common condition in preterm neonates with intraventricular hemorrhage (IVH). Post Hemorrhagic Ventricular Dilatation (PHVD) can lead to lifelong neurological impairment caused by ischemic injury due to increased intracranial pressure, and without treatment can lead to death. Previously, we have developed and validated a 3D ultrasound (US) system to monitor the progression of ventricle volumes (VV) in IVH patients; however, many patients with severe PHVD have ventricles so large they cannot be imaged within a single 3D US image. This limits the utility of atlas based segmentation algorithms required to measure VV as parts of the ventricles are in separate 3D US images, and thus, an already challenging segmentation becomes increasingly difficult to solve. Without a more automated segmentation, the clinical utility of 3D US ventricle volumes cannot be fully realized due to the large number of images and patients required to validate the technique in a clinical trials. Here, we describe the initial results of an automated ‘stitching’ algorithm used to register and combine multiple 3D US images of the ventricles of patients with PHVD. Our registration results show that we were able to register these images with an average target registration error (TRE) of 4.25±1.95 mm.

Paper Details

Date Published: 6 March 2018
PDF: 7 pages
Proc. SPIE 10580, Medical Imaging 2018: Ultrasonic Imaging and Tomography, 1058017 (6 March 2018); doi: 10.1117/12.2292925
Show Author Affiliations
A. Harris, Univ. of Western Ontario (Canada)
S. de Ribaupierre M.D., Univ. of Western Ontario (Canada)
L. Gardi, Univ. of Western Ontario (Canada)
A. Fenster, Univ. of Western Ontario (Canada)
J. Kishimoto, Univ. of Western Ontario (Canada)

Published in SPIE Proceedings Vol. 10580:
Medical Imaging 2018: Ultrasonic Imaging and Tomography
Neb Duric; Brett C. Byram, Editor(s)

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