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Proceedings Paper

MR correlation spectroscopic imaging of multidimensional exponential decays: probing microstructure with diffusion and relaxation
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Paper Abstract

Diffusion-relaxation correlation spectroscopic imaging (DR-CSI) is a novel multidimensional magnetic resonance (MR) imaging approach that we recently introduced for probing microstructure. DR-CSI uses high-dimensional MR data that is acquired with spatial encoding and non-separable diffusion-relaxation contrast encoding, and uses constrained image reconstruction to estimate a spectroscopic image with a multidimensional spectrum for each voxel. The spectral peaks correspond to distinct compartmental microenvironments that coexist within each voxel. This paper reviews DR-CSI and describes and demonstrates its generalization to other contrast mechanisms (i.e., we demonstrate multidimensional relaxation (T1-T2) correlation spectroscopic imaging).

Paper Details

Date Published: 24 August 2017
PDF: 11 pages
Proc. SPIE 10394, Wavelets and Sparsity XVII, 103940D (24 August 2017); doi: 10.1117/12.2272833
Show Author Affiliations
Daeun Kim, The Univ. of Southern California (United States)
Jessica L. Wisnowski, Children's Hospital Los Angeles (United States)
Justin P. Haldar, The Univ. of Southern California (United States)

Published in SPIE Proceedings Vol. 10394:
Wavelets and Sparsity XVII
Yue M. Lu; Dimitri Van De Ville; Manos Papadakis, Editor(s)

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