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Proceedings Paper

Fast frame rate rodent cardiac x-ray imaging using scintillator lens coupled to CMOS camera
Author(s): Swathi Lakshmi B.; M.K.N. Sai Varsha; Ashwin Kumar N.; Madhulika Dixit; Ganapathy Krishnamurthi
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Paper Abstract

Micro-Computed Tomography (MCT) systems for small animal imaging plays a critical role for monitoring disease progression and therapy evaluation. In this work, an in-house built micro-CT system equipped with a X-ray scintillator lens coupled to a commercial CMOS camera was used to test the feasibility of its application to Digital Subtraction Angiography (DSA). Literature has reported such studies being done with clinical X-ray tubes that can be pulsed rapidly or with rotating gantry systems, thus increasing the cost and infrastructural requirements.The feasibility of DSA was evaluated by injected Iodinated contrast agent (ICA) through the tail vein of a mouse. Projection images of the heart were acquired pre and post contrast using the high frame rate X-ray detector and processing done to visualize transit of ICA through the heart.

Paper Details

Date Published: 9 March 2017
PDF: 8 pages
Proc. SPIE 10132, Medical Imaging 2017: Physics of Medical Imaging, 101322K (9 March 2017); doi: 10.1117/12.2254541
Show Author Affiliations
Swathi Lakshmi B., Indian Institute of Technology Madras (India)
M.K.N. Sai Varsha, Indian Institute of Technology Madras (India)
Ashwin Kumar N., Indian Institute of Technology Madras (India)
Madhulika Dixit, Indian Institute of Technology Madras (India)
Ganapathy Krishnamurthi, Indian Institute of Technology Madras (India)

Published in SPIE Proceedings Vol. 10132:
Medical Imaging 2017: Physics of Medical Imaging
Thomas G. Flohr; Joseph Y. Lo; Taly Gilat Schmidt, Editor(s)

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