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Proceedings Paper

Towards practical cost-effective lens-free imaging
Author(s): Abdulkadir Yurt; Richard Stahl; Geert Vanmeerbeeck; Ziduo Lin; Murali Jayapala; Andy Lambrechts
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Paper Abstract

Lens-free holographic microscopy (LHM) is a promising imaging technique for life science and industrial applications, yet system miniaturization and cost reduction without compromising imaging performance remain challenging for field applications in low-resource settings. We demonstrate a cost-effective LHM system without needs for precision optical and mechanical parts (such as lenses, beam-splitters, or kinematic stages) and relies solely on robust optoelectronic hardware and software co-design for high performance imaging. The compact and lightweight form-factor is achieved through integration of light sources, an image sensor and all control electronics with automated calibration and multiwavelength reconstruction algorithms. Amplitude and phase images of a sample can be reconstructed in a few seconds with a micron level optical resolution in a field-of-view of 16.5 mm2. The method offers a portable and scalable solution for microscopic imaging applications.

Paper Details

Date Published: 3 March 2017
PDF: 8 pages
Proc. SPIE 10055, Optics and Biophotonics in Low-Resource Settings III, 100550J (3 March 2017); doi: 10.1117/12.2253237
Show Author Affiliations
Abdulkadir Yurt, IMEC (Belgium)
Richard Stahl, IMEC (Belgium)
Geert Vanmeerbeeck, IMEC (Belgium)
Ziduo Lin, IMEC (Belgium)
Murali Jayapala, IMEC (Belgium)
Andy Lambrechts, IMEC (Belgium)

Published in SPIE Proceedings Vol. 10055:
Optics and Biophotonics in Low-Resource Settings III
David Levitz; Aydogan Ozcan; David Erickson, Editor(s)

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