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Proceedings Paper

High-energy x-ray grating-based phase-contrast radiography of human anatomy
Author(s): Florian Horn; Christian Hauke; Sebastian Lachner; Veronika Ludwig; Georg Pelzer; Jens Rieger; Max Schuster; Maria Seifert; Johannes Wandner; Andreas Wolf; Thilo Michel; Gisela Anton
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Paper Abstract

X-ray grating-based phase-contrast Talbot-Lau interferometry is a promising imaging technology that has the potential to raise soft tissue contrast in comparison to conventional attenuation-based imaging. Additionally, it is sensitive to attenuation, refraction and scattering of the radiation and thus provides complementary and otherwise inaccessible information due to the dark-field image, which shows the sub-pixel size granularity of the measured object. Until recent progress the method has been mainly limited to photon energies below 40 keV. Scaling the method to photon energies that are sufficient to pass large and spacious objects represents a challenging task. This is caused by increasing demands regarding the fabrication process of the gratings and the broad spectra that come along with the use of polychromatic X-ray sources operated at high acceleration voltages. We designed a setup that is capable to reach high visibilities in the range from 50 to 120 kV. Therefore, spacious and dense parts of the human body with high attenuation can be measured, such as a human knee. The authors will show investigations on the resulting attenuation, differential phase-contrast and dark-field images. The images experimentally show that X-ray grating-based phase-contrast radiography is feasible with highly absorbing parts of the human body containing massive bones.

Paper Details

Date Published: 22 March 2016
PDF: 6 pages
Proc. SPIE 9783, Medical Imaging 2016: Physics of Medical Imaging, 97830P (22 March 2016); doi: 10.1117/12.2216893
Show Author Affiliations
Florian Horn, Univ. of Erlangen (Germany)
Christian Hauke, Univ. of Erlangen (Germany)
Sebastian Lachner, Univ. of Erlangen (Germany)
Veronika Ludwig, Univ. of Erlangen (Germany)
Georg Pelzer, Univ. of Erlangen (Germany)
Jens Rieger, Univ. of Erlangen (Germany)
Max Schuster, Univ. of Erlangen (Germany)
Maria Seifert, Univ. of Erlangen (Germany)
Johannes Wandner, Univ. of Erlangen (Germany)
Andreas Wolf, Univ. of Erlangen (Germany)
Thilo Michel, Univ. of Erlangen (Germany)
Gisela Anton, Univ. of Erlangen (Germany)

Published in SPIE Proceedings Vol. 9783:
Medical Imaging 2016: Physics of Medical Imaging
Despina Kontos; Thomas G. Flohr, Editor(s)

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